the activity of the magnocellular neurons (mcns) of supraoptic nucleus (son) is regulated by a variety of excitatory and inhibitory inputs. opioids are one of the important compounds that affect these inputs at son synapses. in this study, whole-cell patch clamp recording of son neurons was used to investigate the effect of acute and repeated morphine administration on spontaneous inhibitory an...

A simple, inexpensive, non-invasive method for urine collection was used in 28 consecutive infants for periods of 48 hours (n = 10) and 72 hours (n = 18). The incidence of urine collector detachment was low on the first and second days (< 4%) and increased significantly on the third day (28%). Volume of urine leaked was < 4% of the total volume collected daily. This method is applicable to both...

BACKGROUND Variation in different urinary measurements for evaluation of iodine status is of concern to clinicians and researchers. OBJECTIVE This study evaluated variations between urine iodine concentration (UIC), spot and 24-h urine sample creatinine concentrations, and 24-h urine iodine excretion (24-h UIE) in repeated samples from school-age children. METHODS Urine samples (24 h and mo...

objective: the present study aimed to determine whether castration altered osmotically stimulated vasopressin (vp) release and urinary volume and what is the role of endocrine-stress axis in this process. materials and methods: totally 108 mice were studied in two main groups of castrated (n=78) and control (n=30). each group was extracted by acute cold stress (4◦c for 2h/day), restraint stress...

[This corrects the article on p. 183 in vol. 58, PMID: 26124849.].

PURPOSE Urine colour (U Col) is simple to measure, differs between low-volume and high-volume drinkers, and is responsive to changes in daily total fluid intake (TFI). However, to date, no study has quantified the relationship between a change in TFI and the resultant change in U Col. This analysis aimed to determine the change in TFI needed to adjust 24-h U Col by 2 shades on an 8-colour scale...